Stress reduces effectiveness of prostate cancer therapies

Washington, January 27 (ANI): Findings from a new study have suggested that beta-blockers, which are used for the treatment of high blood pressure and block the effects of stress hormone adrenaline, could increase the efficacy of anti-cancer therapies.

Prostate cancer patients have increased levels of stress and anxiety; however, several recent studies have found that men who take drugs that interfere with the stress hormone adrenaline have a lower incidence of prostate cancer.

George Kulik and colleagues at Wake Forest University examined the relationship between stress and cancer progression in a mouse model of prostate cancer.

Kulik and colleagues found that mice that had been subjected to stress (exposed to the scent of a predator) exhibited a significantly reduced response to a drug that induces cancer cell death compared to their unstressed counterparts.

Administration of adrenaline also blocked cancer cell death. Conversely, drugs that inhibited adrenaline signaling ablated the effect of stress on prostate cancer.

The finding appeared in the latest issue of the Journal of Clinical Investigation. (ANI)

--

Get stories like this on the Yahoo app and discover more every day.
Download it now.

Matches

    • Team flag for Sri Lanka vs. Team flag for PakistanPAKSL
      5th ODI
      Sun, Jul 26, 2015
      Hambantota, Sri Lanka
      Pakistan in Sri Lanka ODI ...
      SL won by 165 runs
    • Team flag for Netherlands vs. Team flag for ScotlandSCONED
      Final
      Match abandoned
      Sun, Jul 26, 2015
      Malahide, Dublin, Ireland
      World Twenty20 Qualifier, ...
    • Team flag for Hong Kong vs. Team flag for IrelandIREHK
      3rd Place Play-off
      Match abandoned
      Sun, Jul 26, 2015
      Malahide, Dublin, Ireland
      World Twenty20 Qualifier, ...
  • No live matches are in progress.
    • Team flag for England vs. Team flag for AustraliaAUSENG
      3rd Test
      Wed, Jul 29, 2015
      Birmingham, England
      The Ashes, 2015...
      Upcoming match
    • Team flag for Bangladesh vs. Team flag for South AfricaSABAN
      2nd Test
      Thu, Jul 30, 2015
      Mirpur, Bangladesh
      South Africa in Bangladesh...
      Upcoming match
    • Team flag for Sri Lanka vs. Team flag for PakistanPAKSL
      1st T20I
      Thu, Jul 30, 2015
      Thu, Jul 30, 2015
      Colombo, Sri Lanka
      Pakistan in Sri Lanka T20 ...